eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | meningioma |
| Comorbidity | C0020492|hyperostosis |
| Sentences | 7 |
| PubMedID- 20413311 | The precise mechanism of hyperostosis associated with meningioma remains unclear; however, the most widely accepted theory is that the tumor invades the bone. |
| PubMedID- 24497807 | hyperostosis associated with meningiomas is usually localized and proportional to the size of the tumor. |
| PubMedID- 21120550 | The causes of hyperostosis in meningiomas are theorised to include vascular disturbances of the bone caused by the tumour, irritation of the bone without actual invasion, previous trauma, the production of bone by the tumour itself, and the stimulation of osteoblasts in normal bone by factors secreted by tumour cells. |
| PubMedID- 26057993 | In fact, meningioma with calvarial hyperostosis is commonly associated with an increased rate of recurrence if limited bone resection is performed [8]. |
| PubMedID- 24959261 | The following hypotheses concerning the mechanism of hyperostosis associated with meningioma may provide answers to the above questions: preceding trauma; vascular disturbances of the bone caused by the tumor; irritation of the bone by the tumor without invasion; stimulation of osteoblast cells in the normal bone via humoral factors secreted by tumor cells; and formation of bone by the tumor itself (4). |
| PubMedID- 22327326 | Twenty-six meningiomas associated with hyperostosis specimens served as the study group, and 20 meningiomas without any bony changes served as controls. |
| PubMedID- 20809250 | hyperostosis typically indicates infiltration of bone by meningioma [1].fig. |
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