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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease melanoma, malignant
Comorbidity C1261473|sarcoma
Sentences 5
PubMedID- 24168510 Clear cell sarcoma shares features with melanoma, but frequently shows ewsr1 rearrangements.
PubMedID- 22493355 Materials and methods: to evaluate the existence of different molecular aberration patterns in melanoma associated with v-raf murine sarcoma viral oncogene homolog b1 (braf) or 9p21 locus alterations, eleven patient-derived melanoma cell lines were characterized.
PubMedID- 20087159 Clear cell sarcoma (ccs) of tendons and aponeuroses/malignant melanoma (mm) of soft parts is a rare tumor and in the majority of cases presents a characteristic reciprocal translocation t(12;22)(q13;q12) that results in fusion of the ews and atf1 genes.
PubMedID- 22948772 Isolated limb perfusion (ilp) with recombinant human tumor necrosis factor-α (rhtnf-α, or tasonermin) and melphalan is a highly effective treatment for soft tissue sarcoma and in-transit metastases of malignant melanoma of the extremities.
PubMedID- 25898411 Morphologists once classified clear cell sarcoma as a type of malignant melanoma, based on finding melanosomes within tumor cells.

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