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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease melanoma, malignant
Comorbidity C0042900|vitiligo
Sentences 13
PubMedID- 22908963 Serum dppiv activity in healthy controls (c), in people with vitiligo (v), in patients with melanoma (m), and in patients with other malignant skin tumors (mst) or benign skin changes (bs).
PubMedID- 25834362 However, the prognostic value of vitiligo in melanoma was reported to be inconsistent among previous reports.
PubMedID- 25605840 vitiligo-like depigmentation in patients with stage iii-iv melanoma receiving immunotherapy and its association with survival: a systematic review and meta-analysis.
PubMedID- 23136900 Recent genetic studies suggest a lower susceptibility to melanoma in patients with vitiligo; however, lifetime melanoma prevalence in patients with vitiligo has not previously been studied.
PubMedID- 21794122 The occurrence of vitiligo in melanoma patients undergoing immunotherapy may be due to both qualitative and quantitative differences between the cd8+ t cells in the two diseases.
PubMedID- 25242557 Objective: we sought to study the relative risk (rr) of melanoma and nmsc in patients with vitiligo compared with that in patients seen for vascular surgery.
PubMedID- 25702668 Association of vitiligo and response in patients with metastatic malignant melanoma on temozolomide.
PubMedID- 24366614 Additionally, association of vitiligo with immunotherapy of melanoma employing activated cytotoxic t cells specific for shared tumor antigens and melanosomal proteins further supports the autoimmune etiology of vitiligo(mehrotra et al., 2012; sakai et al., 1997; yee et al., 2000).
PubMedID- 22561518 The associated region contains 20 genes, notably including mc1r, encoding the melanocortin receptor, a regulator of melanogenesis and minor vitiligo autoantigen, associated with malignant melanoma and with skin and hair color20.
PubMedID- 23887251 Cutaneous vitiligo following management of uveal melanoma in 6 patients.
PubMedID- 24082190 The occurrence of vitiligo like lesions in patients with metastatic melanoma in comparison has a better prognosis.
PubMedID- 20498710 Successful melanoma immunotherapy can lead to treatment-related vitiligo-like leukoderma as an autoimmune side-effect [18], which is considered an encouraging prognostic sign [19], [20].
PubMedID- 21909283 Waardenburg syndromes), differentiation (albinism), survival (vitiligo) or control of proliferation (melanoma) [6].

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