eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | melanoma, malignant |
| Comorbidity | C0028754|obesity |
| Sentences | 4 |
| PubMedID- 24600206 | Our results indicate that combinations of inhibitors of the pi3k/akt pathway and dtic or braf inhibitors may be useful to improve the therapeutic efficacy in the treatment of melanoma, in particular, in patients with obesity and type ii diabetes who have elevated serum insulin levels. |
| PubMedID- 22450736 | Objective: to conduct a prospective study to examine the association between obesity and the risk of both melanoma and non-melanoma skin cancers. |
| PubMedID- 22686498 | obesity, location of the primary melanoma at a distal site on the leg, a wide safety margin, and seromas are associated with postoperative leg swelling. |
| PubMedID- 21387314 | We provide strong evidence that diet-induced obesity leads to increased melanoma progression in male c57bl/6j mice. |
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