Disease | melanoma, malignant |
Comorbidity | C0027962|melanocytic nevi |
Sentences | 15 |
PubMedID- 24433184 | Semiquantitative evaluation of this expression revealed downregulated expression of rpe65 in malignant melanoma compared with benign melanocytic nevi (p < 0.001). |
PubMedID- 23739702 | The risk of cutaneous melanoma in melanocytic nevi. |
PubMedID- 20086181 | We aimed to estimate the population attributable fraction (paf) for melanoma associated with melanocytic nevi using relative risk estimates derived from a systematic review and meta-analysis. |
PubMedID- 23785613 | When clark in 1969 described the types of melanoma currently recognized, he noted that origin of melanoma from a nevus was “the exception rather than the rule.” [4] fifteen years later, in order to satisfy the concept of multistep carcinogenesis, he returned to the position that melanomas resulted from transformation of melanocytic nevi in what he called “six evident lesional steps of tumor progression,” namely, “1) the common acquired melanocytic nevus; 2) a melanocytic nevus with lentiginous melanocytic hyperplasia, i.e., aberrant differentiation; 3) a melanocytic nevus with aberrant differentiation and nuclear atypia, i.e., melanocytic dysplasia; 4) the radial growth phase of primary melanoma; 5) the vertical growth phase of primary melanoma; and 6) metastatic melanoma.” in regard to melanoma, he contended that “the radial growth phase is . |
PubMedID- 21155082 | Results and conclusions: with regard to the reported cases, melanomas associated with melanocytic nevi were mainly superficial spreading melanomas and nodular melanomas on the trunk or extremities; alms were rarely associated with nevi, indicating a trend similar to that observed in caucasians. |
PubMedID- 22550586 | The magnitude of the shift reflects the local stiffness of the tissue, which has shown promising results when comparing benign melanocytic nevi with melanoma [37]. |
PubMedID- 26528046 | In the first part of the study we compared the changes which occurred in melanomas with those in melanocytic nevi (dysplastic and common nevi). |
PubMedID- 19830692 | Mir-15b and mir-210 were significantly upregulated, mir-34a was significantly downregulated in melanomas compared with melanocytic nevi. |
PubMedID- 21876460 | Altered expression of stat3 mrna, pstat3, and socs3 protein was observed in melanoma specimens, compared with benign melanocytic nevi. |
PubMedID- 24842760 | We also characterize the frequency of braf mutations in female genital tract melanomas compared with melanocytic nevi. |
PubMedID- 21737053 | They also indicate a higher frequency of superficial spreading melanomas and melanomas associated with melanocytic nevi in patients carrying certain mutations in mc1r. |
PubMedID- 25692084 | In one study, bolognia et al concluded that “a small percentage of ‘small dark dots’ within melanocytic nevi are due to melanoma”, finding 3 (5%) of 59 such nevi to be melanoma [3]. |
PubMedID- 22906024 | Nevertheless, further studies are needed to validate the functional role of 14-3-3 proteins in melanotumorigenesis through the proteomic comparison of different malignant melanoma patients with giant congenital melanocytic nevi. |
PubMedID- 22464597 | They also indicate a higher frequency of superficial spreading melanomas and melanomas associated with melanocytic nevi in patients carrying certain mutations in mc1r. |
PubMedID- 24672253 | There have been reports of histological atypia (pseudomelanoma) in patients with melanocytic nevi that were treated by co2 lasers as well as lasers for hair removal.33 racial differences probably also need to be taken into consideration, as in asians, the incidence of melanoma has been reported to be between 0.2 and 2.2 per 100,000, much lower than among whites.34 furthermore, the most common sites for the development of melanoma among people with skin of color are areas not directly exposed to the sun, such as palmar, plantar, subungual, and mucosal surfaces.34 this may account for the liberal use of lasers for the treatment of melanocytic nevi in asian countries on the facial skin. |
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