eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | melanoma, malignant |
| Comorbidity | C0025202|melanomas |
| Sentences | 10 |
| PubMedID- 24406374 | For instance, nodular melanomas (~15% of cutaneous melanoma) grow vertically from the beginning and present a necrotic core12. |
| PubMedID- 22084644 | Conclusions: elderly (>/=70 yrs) melanoma patients present with thicker melanomas and a higher mitotic rate but have fewer sln metastases. |
| PubMedID- 25433395 | Mitf e318k has been described as a medium-penetrance gene in melanoma associated with multiple primary melanomas developed in its carriers [50, 51], and as predisposing to renal carcinoma as well [48]. |
| PubMedID- 22570796 | Recent data suggest multiple pathways of melanoma pathogenesis, with melanomas in sun-protected skin (trunk) developing in association with a high nevus count and intermittent ultraviolet radiation as opposed to those developing on sun-exposed skin in patients with low nevus counts and chronic sun exposure [17, 18]. |
| PubMedID- 21423681 | Adam10 expression was significantly elevated in melanoma metastases compared with primary melanomas [14]. |
| PubMedID- 24885594 | One-hundred twelve patients with histologically-proven diagnosis of multiple melanoma (96 cases with two primary melanomas, 15 with three, and 1 with four) were included into the study. |
| PubMedID- 25909885 | Moreover, gmps levels are increased in metastatic human melanoma specimens compared with primary melanomas arguing that gmps is an attractive candidate for anti-melanoma therapy. |
| PubMedID- 22848838 | Diagnostic source was also significantly related to a family history of melanoma, with significantly more melanomas identified by patients when there was a family history of melanoma (di = 7%, pi = 23%) compared to no family history (di = 67%, pi = 55%), or a family history of other skin cancers (di = 26%, pi = 22%), (χ2 = 9.7, p < 0.01). |
| PubMedID- 25194935 | Conclusions: dietary choices at the time of diagnosis are associated with melanoma-specific survival in patients with melanomas more than 1.00 mm thick. |
| PubMedID- 21064111 | In conclusion, the patient's age is a strong and independent predictor of melanoma-specific survival in patients with localized melanomas, in patients with positive slns and after the onset of distant metastases. |
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