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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease malaria
Comorbidity C0037054|sickle cell trait
Sentences 3
PubMedID- 24426355 We present a case of sickle cell trait infected with severe falciparum malaria unbalancing of balanced polymorphism.
PubMedID- 25805752 The disease has also exerted significant selection pressure on the human genome, as evidenced by the congruence of malaria parasite prevalence with sickle cell trait (hbas) and other hemoglobinopathies, such as thalassemias and glucose-6-phosphate dehydrogenase (g6pd) deficiency.
PubMedID- 22273840 Falciparum malaria in a patient with sickle cell trait with hemophagocytosis and secondary pancytopenia.

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