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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease malaria
Comorbidity C0017920|g6pd deficiency
Sentences 8
PubMedID- 23384623 The spatial extent of plasmodium vivax malaria overlaps widely with that of g6pd deficiency; unfortunately the only drug licensed for the radical cure and relapse prevention of p.
PubMedID- 23152723 g6pd deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map.
PubMedID- 25678925 Conclusion: vivax malaria positive individuals with g6pd deficiency showed too mild symptoms of malaria or even asymptomatic.
PubMedID- 23175557 In conclusion, the study of sutanto and colleagues clearly demonstrates the efficacy and safety of a single dose of 0.45 mg/kg primaquine on the third day of treatment as a gametocytocide drug in the treatment of uncomplicated falciparum malaria, excluding patients with g6pd deficiency.
PubMedID- 20684792 The fact that the prevalence of g6pd deficiency correlates with endemicity for malaria had lead to the hypotheses that g6pd deficiency may be result of natural selection conferring protection against malaria infection [2-5].
PubMedID- 24502194 Clinical mppt investigations revealed that malaria patients with g6pd deficiency tolerated primaquine much better than non-infected persons with the deficiency.
PubMedID- 20520804 The frequency of phenotypic and genotypic g6pd deficiency in individuals with vivax malaria was compared against controls who had not had malaria in the previous two years.
PubMedID- 22171972 Despite numerous evidences on the protection of p. falciparum malaria in g6pd deficiency patients, the high failure rate following treatment with standard anti-malarial regimen is still high [33].

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