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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease malaria
Comorbidity C0002871|anemia
Sentences 46
PubMedID- 24450283 Severe anemia accounts for half of all malarial deaths in african children and women, co-infection with malaria and intestinal worms has been shown to result in greater anemia.
PubMedID- 24834053 Makes several key predictions that support a role for erythropoiesis in driving the protection from malaria associated with iron deficiency anemia and increased risk associated with iron supplementation.
PubMedID- 21075280 Other factors, including response to anemia, and the influence of infection with malaria and other environmental influences, may be important.
PubMedID- 24358031 Background: the burden of anemia attributable to non-falciparum malarias in regions with plasmodium co-endemicity is poorly documented.
PubMedID- 22752514 Acidosis in severe malaria has been associated with severe anemia and respiratory distress or deep breathing and is an established strong predictor of mortality in adult as well as pediatric severe malaria [31, 37].
PubMedID- 24050302 In bolivia, the paf of moderate-to-severe anemia associated with p. vivax malaria was 3.5%, and the paf for low birthweight was 6.1% for p. vivax.
PubMedID- 25221716 anemia in children with malaria may require blood transfusion and has been be associated with high mortality rates.
PubMedID- 25928774 We also did not observe a protective effect between baseline anemia and the risk of developing malaria as has been suggested elsewhere [41].
PubMedID- 24237997 Independent of hiv, maternal malaria is associated with anemia and maternal mortality [56-58].
PubMedID- 22287859 The demand for blood transfusion is high in sub-saharan africa because of the high prevalence of anemia especially due to malaria and pregnancy-related complications.
PubMedID- 25567973 For example, the characteristic anemia associated with malaria infection is driven by a combination of destruction of infected rbcs by parasites, as well as haemolysis (ritter et al.
PubMedID- 22094132 Whereas epo ameliorates hemolytic anemia in malaria or trypanosomiasis and improves the course of autoimmune diseases such as inflammatory bowel disease or autoimmune encephalomyelitis, it deleteriously inhibits macrophage functions in salmonella infection in animal models.
PubMedID- 25889703 Asymptomatic malaria was significantly associated with anemia among the pregnant women.
PubMedID- 21072315 Prevalence of anemia in women with asymptomatic malaria parasitemia at first antenatal care visit at the university of calabar teaching hospital, calabar, nigeria.
PubMedID- 25807235 Moreover, excessive hemolysis of parasitized rbcs in malaria infection may lead to anemia [9].
PubMedID- 24517107 In the pediatric ward, anemia due to malaria was the main indication for transfusion, followed by sickle cell vaso-occlusive crisis.
PubMedID- 22826498 Twenty-one percent, 15%, 12%, 11% and 7% of anemia were attributable to malnutrition, malaria, iron, folic acid deficiencies, and helminth infestations, respectively.
PubMedID- 23382166 Overall 16.8% of anemia cases were associated with malaria, 8.3% with iron deficiency, and 6.1% with inflammation.
PubMedID- 22131906 The question of whether the synesthesia gene(s) may have a “hidden agenda” like the sickle cell anemia gene has with malaria resistance, and whether that agenda may be “creativity and metaphor”, was first raised by ramachandran and hubbard [15].
PubMedID- 23490427 Additional strategies to improve sp coverage may reduce the lbw and maternal anemia associated with malaria in pregnancy.
PubMedID- 21738863 Both clinical and asymptomatic malaria have been associated with anemia of inflammation.
PubMedID- 25898007 Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, france, 2011-2013.
PubMedID- 23573367 Moreover, malaria induced anemia was studied in comparison with anemia induced by hemorrhage and hemolysis.
PubMedID- 24550911 Of all the plasmodium species infecting humans, p. falciparum is the most virulent and its pathology is characterized by severe anemia or the development of cerebral malaria, generally leading to death if left untreated (3).
PubMedID- 24218409 There were certain outlier costs, such as in 2005, when cerebral malaria with anemia and malaria with severe anemia cost on average more than severe malaria.
PubMedID- 24007344 Abrams et al., [32] however found that malaria infection was associated with low anemia among pregnant mothers but not fetal hemoglobin.
PubMedID- 20196168 Common causes of anemia in malaria-infected children, such as increased parasitemia or reduced erythropoiesis, did not account for worsening anemia in the hiv-1(+)/pf(+) group nor did carriage of sickle cell trait or g6pd deficiency.
PubMedID- 24587473 Our findings are also consistent with research suggesting that in the context of low socio-demographic status, even light infections such as hookworm and malaria may be associated with anemia [27], [52]; however, further research is needed to address these relationships.
PubMedID- 21529383 Known and possible causes of hemolytic anemia in association with malaria or antiparasitic therapy include blackwater fever, artemisinin-induced reticulocytopenia, direct hemolytic effects of the drug, and drug-induced immune hemolytic anemia.
PubMedID- 21504595 This may especially be relevant in settings with high prevalence of anemia due to malaria and nutritional deficiencies where zidovudine can't be readily used.
PubMedID- 22506087 anemia, a hallmark of both vl and malaria, negatively correlated with the co-occurrence of malaria in vl patients.
PubMedID- 23113116 Many adverse aftermaths including, low birth weight, intrauterine growth retardation, preterm delivery, stillbirth and anemia were found associated with malaria in pregnant women.
PubMedID- 23945350 anemia in malaria is multifactorial and mainly due to haemolysis and dyserythropoiesis [39].
PubMedID- 21479575 malaria infection leads to anemia in humans which generally occurs during the chronic phase of the infection.
PubMedID- 24358185 Severe anemia associated with malaria was defined as hgb<6 g/dl and a positive smear.
PubMedID- 25884992 Hiv increases the degree to which malaria is associated with severe anemia and low birth weight beyond the effect of hiv itself on these outcomes.
PubMedID- 20386613 Several mechanisms seem to contribute to anemia during malaria, with pronounced differences in different patient populations and animal models.
PubMedID- 24575278 Pthophysiologic mechanisms of anemia in malaria is such as direct invasion of red cells, anemia of chronic disease hypersplenism, hemophagocytic syndrome and erythrophagocytosis, dyserythropoirsis, immune haemolysis and cytokine deregulation anemia of chronic disorder is characterized by moderate to mild normocytic, normochromic anemia along with microcytic hypochromic cells.
PubMedID- 20859503 In asplenic, elderly, or immunocompromised patients a severe malaria-like illness with hemolytic anemia and renal failure can occur.
PubMedID- 25604792 malaria induces anemia through cd8+ t cell-dependent parasite clearance and erythrocyte removal in the spleen.
PubMedID- 24520208 The majority of recipients in emerging countries are younger and more likely to be women and children.53 transfusion most frequently occurs because of acute blood loss from injury and obstetric hemorrhage, which are best treated with fresh whole blood, and for childhood anemia due to malaria.54 the who recommends whole blood for malaria,55 in which metabolic acidosis and hypovolemia56 may be ameliorated by the fresh plasma portion.
PubMedID- 23620856 Objective: to assess the prevalence of anemia in children with urinary schistosomiasis, malaria and concurrent infections by the two diseases.
PubMedID- 22888709 anemia was significantly associated with asymptomatic malaria infection among hiv patients on haart with an odd ratio of 16.47 (95%: ci: 0.919, 295.5; p = 0.021).
PubMedID- 26384816 Treatment of iron deficiency anemia in malaria endemic areas is complicated as iron supplementation increases malaria risk while malaria decreases iron absorption.
PubMedID- 20505829 malaria was strongly associated with anemia which is consistent with previous reports [5], [27], [28].
PubMedID- 26465787 Severe hemolytic anemia in malaria is caused by the destruction of host rbcs following plasmodium parasite growth and, to a greater extent, by the elimination of uninfected rbcs [10, 12, 37].

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