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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease macular degeneration
Comorbidity C0456909|vision loss
Sentences 27
PubMedID- 22885784 Currently, no effective treatment can reverse the central vision loss associated with most age-related macular degeneration.
PubMedID- 21851170 Purpose: choroidal neovascularization (cnv) is a major cause of vision loss in patients with age-related macular degeneration (amd).
PubMedID- 19895863 Choroidal neovascularization (cnv) is the major cause of severe vision loss in patients with age-related macular degeneration (amd).
PubMedID- 22702841 Age-related macular degeneration (amd) can lead to irreversible central vision loss in the elderly.
PubMedID- 22629470 The data obtained are important for deciphering the putative link between cholesterol and age-related macular degeneration, a major cause of irreversible vision loss in the elderly.
PubMedID- 20879805 At a later stage, neovascular or exudative age-related macular degeneration can lead to severe central vision loss that is related to aging-associated cumulative oxidative stress of the human retinal pigment epithelium (hrpe) cells.
PubMedID- 22499498 Geriatric vision loss due to cataracts, macular degeneration, and glaucoma.
PubMedID- 21609233 Retinal pigment epithelial detachment (ped) is an important predictor of vision loss in patients with age-related macular degeneration (amd).
PubMedID- 23440797 Background: neovascular age-related macular degeneration (amd) is associated with rapid vision loss due to choroidal neovascularization (cnv), leakage, and scarring.
PubMedID- 24664714 Purpose: degeneration or dysfunction of the retinal pigment epithelium (rpe) can induce secondary photoreceptor atrophy and catastrophic vision loss in patients with age-related macular degeneration (amd).
PubMedID- 25748723 Among dietary carotenoids, lutein and zeaxanthin are known to protect against age-related macular degeneration, a leading cause of irreversible vision loss in the elderly.
PubMedID- 25922843 Stargardt disease (stgd) is the leading cause of juvenile macular degeneration associated with progressive central vision loss, photophobia, and colour vision abnormalities.
PubMedID- 21199624 A 79-year-old female had vision loss due to wet age-related macular degeneration, corneal endothelial dystrophy with corneal oedema and cataract.
PubMedID- 24036952 Age-related macular degeneration (amd) leads to irreversible vision loss in individuals over 55 years of age1-3.
PubMedID- 21690377 Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration.
PubMedID- 21035124 Recent interest in the role played by vlc-pufa arose from the findings that a protein called elongation of very-long-chain fatty acids 4 (elovl4) is involved in their biosynthesis and that mutations in the elovl4 gene are associated with stargardt-like macular dystrophy (std3), a dominantly inherited juvenile macular degeneration leading to vision loss.
PubMedID- 20631844 A better understanding of the neural mechanisms for reliability-weighted multisensory integration may help in the development of treatment and rehabilitation strategies for the many disorders in which the information from a sensory modality is degraded, such as vision loss due to macular degeneration.
PubMedID- 22570607 The neovascular (wet) form of age-related macular degeneration (amd) leads to vision loss due to choroidal neovascularization (cnv).
PubMedID- 21142375 This study used vision loss due to age-related macular degeneration to learn about adaptation processes related to chronic functional impairment, focusing on horowitz and reinhardt's (1998) concept of adaptation to age-related vision loss (avl) as the outcome.
PubMedID- 25893842 To investigate this question, we examined visual long-term memory for objects in patients suffering from foveal vision loss due to age-related macular degeneration.
PubMedID- 25578255 Pigment epithelial detachment followed by retinal cystoid degeneration leads to vision loss in treatment of neovascular age-related macular degeneration.
PubMedID- 25646102 While new biologics have revolutionized the treatment of age-related macular degeneration-the leading cause of severe vision loss among older adults-these new drugs have also raised concerns over the economic impact of medical innovation.
PubMedID- 22438952 This vascular pathology is most classically seen in exudative or “wet” age-related macular degeneration, the leading cause of vision loss in the western world [13]–[14].
PubMedID- 21858086 We moreover examined the effects of p4-tat on choroidal neovascularization (cnv), which is the main cause of severe vision loss in patients with age-related macular degeneration [32], by the use of laser-induced choroidal neovascularization in mice [17], [18].
PubMedID- 25573059 Choroidal neovascularization (cnv) is the main pathogenesis of age-related macular degeneration (amd), which leads to severe vision loss in many aged patients in most advanced country.
PubMedID- 21951567 Outcomes following three-line vision loss during treatment of neovascular age-related macular degeneration: subgroup analyses from marina and anchor.
PubMedID- 24978868 Purpose: when individuals with central vision loss due to macular degeneration (md) view stimuli in the periphery, most of them activate the region of retinotopic cortex normally activated only by foveal stimuli-a process often referred to as reorganization.

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