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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease lysosomal acid lipase deficiency
Comorbidity C0010068|coronary artery disease
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PubMedID- 26225414 The morbidity of late-onset cesd results from atherosclerosis (coronary artery disease, stroke), liver disease (e.g., altered liver function +/- jaundice, steatosis, fibrosis, cirrhosis and related complications of esophageal varices, and/or liver failure), complications of secondary hypersplenism (i.e., anemia and/or thrombocytopenia), and/or malabsorption.

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