eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | lymphoblastic leukemia |
| Comorbidity | C0376545|hematologic malignancies |
| Sentences | 1 |
| PubMedID- 24513123 | This review analyzes the studies indicating that cd123 is overexpressed in various hematologic malignancies, including a part of acute myeloid and b-lymphoid leukemias, blastic plasmocytoid dendritic neoplasms (bpdcn) and hairy cell leukemia.given the low/absent cd123 expression on normal hematopoietic stem cells, attempts have been made at preclinical first, and then at clinical level to target this receptor. |
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