eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | li-fraumeni syndrome |
| Comorbidity | C1621958|glioblastoma multiforme |
| Sentences | 1 |
| PubMedID- 24156637 | Of interest in this regard is the recent identification, in glioblastoma multiforme, of a mir/tp53 feedback autoregulatory circuit involving expression of p53, e2f1 and myc to regulate expression of mir-25, which in turn controls p53 accumulation [65], most likely via direct targeting of the 3′utr region of tp53 [97]. |
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