eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | li-fraumeni syndrome |
| Comorbidity | C0027819|neuroblastoma |
| Sentences | 2 |
| PubMedID- 25658463 | neuroblastoma cell lines with wild-type tp53 alleles were highly sensitive to gsk2830371 treatment, while cell lines with mutant tp53 were resistant to gsk2830371. |
| PubMedID- 24173829 | We have also shown that s(+)-ibuprofen was growth suppressive to neuroblastoma cell lines with a tp53 mutation, though the efficacy was less compared to those with no tp53 mutation. |
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