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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease leukemia, acute myeloid
Comorbidity C1261473|sarcomas
Sentences 2
PubMedID- 24791856 We report a humanized experimental leukemia model where xenografts develop aggressive acute myeloid leukemia (aml) with disseminated myeloid sarcomas within 4 weeks following transplantation of cord blood transduced with vectors expressing bcr-abl1 and a dominant-negative isoform of ikaros, ik6.
PubMedID- 23580888 They are also known as chloromas, myeloblastomas, myelocytomas, chloroleukemia and granulocytic sarcomas and are associated with acute myeloid leukemia (aml) and blastic transformation of chronic myeloproliferative disorders (chronic myeloid leukemia, polycythemia vera and primary myelofibrosis) and myelodysplastic syndromes.

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