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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease leukemia, acute myeloid
Comorbidity C0030312|bone marrow failure
Sentences 3
PubMedID- 21196392 The relative risk of clonal evolution to either myelodysplasia (mds) or acute myelogenous leukemia (aml) is high in patients with chronic bone marrow failure.
PubMedID- 22504776 Fanconi anemia (fa) is a rare recessive dna repair disorder that is clinically characterized by congenital malformations, progressive bone marrow failure, and increased incidence of malignancies, especially acute myeloid leukemia and squamous cell carcinomas of the head and neck (hnsccs) and the anogenital regions.
PubMedID- 22965917 Background: fanconi anemia (fa) is a rare autosomal recessive genetic disorder characterized by bone marrow failure and increased risk of cancers including acute myelogenous leukemia and various solid tumors, especially head and neck cancer.

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