eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | leptospirosis |
| Comorbidity | C0040034|thrombocytopenia |
| Sentences | 5 |
| PubMedID- 25252528 | leptospirosis typically presents with fever and thrombocytopenia, with or without jaundice. |
| PubMedID- 24311548 | Arf, hyperbilirubinaemia, acute respiratory distress syndrome (ards), creatine kinase (ck) elevation and thrombocytopenia were predictors of death in leptospirosis and thrombocytopenia, ards and arf predictors of death in dengue. |
| PubMedID- 24519201 | thrombocytopenia in leptospirosis is known to be associated with a worse prognosis 9. tantitanawat and tanjatham 28 found that platelet counts <100,000/mm3 were an independent risk factor for death in leptospirosis. |
| PubMedID- 24444080 | In our study, the platelet count was reduced in both dengue and leptospirosis, with more profound thrombocytopenia in dengue fever. |
| PubMedID- 25467300 | Conclusion: we suggest that hemophogocytosis is a possible mechanism of thrombocytopenia in leptospirosis and that examination of bone marrow should be performed to confirm the diagnosis. |
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