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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease keratitis
Comorbidity C0085109|corneal neovascularization
Sentences 3
PubMedID- 22050866 Five animals had superficial ulcerative keratitis with intense corneal neovascularization and edema.
PubMedID- 25754842 The herpes viruses including hsv-1, varicella zoster virus (vzv) and cytomegalovirus (cmv) are the common cause of viral keratitis that leads to corneal neovascularization 26. ebv is also detected in patients underwent cornea transplantation and viral keratitis 27. ebv infection of human b lymphocytes often leads to latency, a state in which most viral genes are not expressed 28. however, ebv-encoded small rnas (ebers), the most abundant small non-coding rnas, are detected in human cells infected with ebv 29. epithelial cells are a dominant and widespread source of pro-inflammatory cytokine il-32 30. however, it is still unclear how il-32 induces other inflammatory cytokines after corneal viral infection and what signalling pathways are involved in secretion of anti-viral type i interferon.
PubMedID- 22840481 Purpose: to quantify changes in corneal neovascularization in patients with active keratitis after treatment using color imaging, fluorescein angiography (fa), and indocyanine green angiography (icga).

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