eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | kennedy disease |
| Comorbidity | C0028754|obesity |
| Sentences | 3 |
| PubMedID- 23950976 | Methods: 9 snps in biological candidate genes showing replications (pparg, adrb3, adrb2, lepr, gnb3, ucp3, adipoq, ucp2, and nr3c1), and 17 snps in or near genes associated with obesity in first, second and third wave gwas (insig2, fto, mc4r, tmem18, faim2/bcdin3, bdnf, sh2b1, gnpda2, negr1, kctd15, sec16b/rasal2, npc1, sfrf10/etv5, maf, prl, mtch2, and pter) were genotyped in 1,156 unrelated mexican-mestizos including 683 cases (441 obese class i/ii and 242 obese class iii) and 473 normal-weight controls. |
| PubMedID- 22761590 | These regions were found near genes associated with obesity (mcr4, figure s11), imprinting (gnas, figure s12), and glial cell formation (metrnl, figure s13). |
| PubMedID- 25800470 | Conclusion: w64r polymorphism of the beta-3ar gene is not associated with obesity and waist-to-hip ratio in turkish children. |
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