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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease kennedy disease
Comorbidity C0011570|depression
Sentences 2
PubMedID- 26471432 Conclusions: remission to antidepressants in geriatric depression may be associated with a particular gene expression profile in monoaminergic and metabolic pathways and needs to be replicated in a larger sample.
PubMedID- 22832399 Particularly neuroticism has been shown to have a clear genetic overlap with major depression and to predict the subsequent onset of the disorder.9 furthermore, as neuroticism reflects a tendency to cope poorly with stress,9 hpa axis (dys)function may be involved in this association.

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