eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | kennedy disease |
| Comorbidity | C0006142|breast cancer |
| Sentences | 3 |
| PubMedID- 22514728 | Here, we present evidence that myoepithelial lineage restricted k5−/k19− myoepithelial progenitor cells (mpcs) derived from bipotent k5+/k19− stem/progenitor cells share a molecular gene expression signature with claudin-low breast cancer subtype. |
| PubMedID- 25531321 | The molecular genetic mechanisms that lead to radiogenic breast cancer are unclear, but there is evidence that cancers subsequent to radiation exposure have genotypic and phenotypic features that distinguish them from other breast cancers, and are more likely to be of the her2 or basal-like subtypes.10 furthermore, array comparative genomic hybridisation and expression microarray analyses demonstrate that radiogenic breast cancers cluster separately from other breast cancers10,11 and have a higher degree of genetic instability, such as a higher frequency of allelic loss of chromosome bands 6q13–q14 and 9p21.12,13 specific alterations have been implicated in radiogenic breast transformation,14-18 but there is no evidence that any of these genetic changes are induced directly by radiation exposure. |
| PubMedID- 21106486 | One such example can be found in the paper by ochs-balcom et al., in which the authors looked at the association of breast cancer with a particular gene of interest [33]. |
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