eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | intestinal disease |
| Comorbidity | C0235974|pancreatic carcinoma |
| Sentences | 1 |
| PubMedID- 25818486 | Recent evidence suggests that both nox1 and duox2 species produce ros in the gastrointestinal tract as a result of chronic inflammatory stress; cytokine induction (by interferon-gamma, tumour necrosis factor alpha, and interleukins il-4 and il-13) of nox1 and duox2 may contribute to the development of colorectal and pancreatic carcinomas in patients with inflammatory bowel disease and chronic pancreatitis, respectively. |
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