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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease intestinal disease
Comorbidity C0162429|poor nutrition
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PubMedID- 24455429 One putative mechanism is a direct toxicity of aflatoxin on the integrity of the intestine [137], and it is plausible that gastrointestinal bacterial infections, a major cause of growth faltering [129, 130, 138–143], and aflatoxins either additively or synergistically cause prolonged gastrointestinal enteropathy leading to poor nutritional uptake and nutrition retention, in regions where diets are frequently “nutritionally poor.” cotoxicities of xenobiotics and infections are an increasingly emerging area of concern [144] in the etiology of chronic disease, and it is already established that aflatoxins and hepatitis b virus play a synergistic role in the high incidence of hepatocellular carcinoma in certain world regions [145–149].

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