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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease iga nephropathy
Comorbidity C1565489|renal insufficiency
Sentences 3
PubMedID- 21422741 Many lessons have been learnt from this experimental model; importantly, that glomerular hyperfiltration, hyperfusion, hypertension, and hypertrophy are associated with the progression of glomerulosclerosis.4,5) other experimental models of progressive glomerulonephrits, such as the accelerated form of anti-glomerular basement membrane nephritis characterized by destructive or crescentic glomerular lesions, differ substantially from the pathohistological features of the gradually accumulating mesangial matrix seen in human diabetic nephropathy and iga nephropathy, eventually leading to chronic renal insufficiency.
PubMedID- 24602173 Relationship analysis indicated that urinary and tissue sgk1 expressions were associated with heavy proteinuria and renal insufficiency in patients with iga nephropathy.
PubMedID- 24950582 His past medical history included ischemic cardiomyopathy, atrial fibrillation, renal insufficiency due to iga nephropathy and c virus chronic hepatitis.

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