eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hypothyroidism |
| Comorbidity | C1145670|respiratory failure |
| Sentences | 2 |
| PubMedID- 25473574 | The mechanisms of type ii respiratory failure due to hypothyroidism include (1) impaired central ventilator responses to hypoxia and hypercapnia; (2) hypoventilation caused by respiratory muscle dysfunction; and (3) obstructive sleep apnea syndrome (osas) [1]. |
| PubMedID- 21867529 | Ttf-1 haploinsufficiency secondary to deletions or mono-allelic mutations of the nkx2.1 gene has been recognized as a rare cause of neonatal or infantile respiratory failure, often associated with congenital hypothyroidism and/or benign hereditary chorea [16-20], referred to as "brain-lung-thyroid syndrome". |
Page: 1