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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hypokalemia
Comorbidity C0004775|bartter syndrome
Sentences 4
PubMedID- 21626220 Inhibition of cox-2 also reduces hyper-reninism and hypokalemia in patients with antenatal bartter syndrome.
PubMedID- 25619794 bartter syndrome is associated with salt wasting, hypokalemia, metabolic alkalosis, and increased renin secretion and is caused by inactivating mutations in genes encoding ion channels and transporters that mediate salt transport in the thick ascending limb of the loop of henle [6].
PubMedID- 24039833 Ksp-osr1−/− mice exhibited a bartter syndrome-like phenotype with significant hypokalemia due to excessive renal k+ secretion and hypercalciuria.
PubMedID- 22282380 The severe, steady-state hypokalemia in bartter syndrome and gitelman syndrome may abruptly become life-threatening under certain aggravating conditions.

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