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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hypoadrenalism
Comorbidity C0023895|liver disease
Sentences 4
PubMedID- 21712512 This case highlights rapid onset of adrenal insufficiency in a patient with cf-related liver disease treated briefly with a moderate cyp3a4 inhibitor.
PubMedID- 20347173 The elevated levels of bile acids arising during cholestasis may contribute to the down-regulation of the hpa axis and hence the apparent adrenal insufficiency associated with liver disease.
PubMedID- 24661563 It is worth mentioning that relative adrenal insufficiency is common in patients with liver disease.
PubMedID- 21111993 The presence of relative adrenal insufficiency in patients with end-stage liver disease may have therapeutic implications in patients admitted with acute-on-chronic liver failure.

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