eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperuricemia |
| Comorbidity | C0022658|nephropathy |
| Sentences | 3 |
| PubMedID- 23897192 | Familial chronic interstitial nephropathy with hyperuricaemia caused by the umod gene. |
| PubMedID- 22701621 | In this study, we used streptozotocin (stz)-induced diabetic nephropathy model with hyperuricemia and dyslipidemia in rats, and found over-expression of renal inflammasome components nlrp3, apoptosis-associated speck-like protein and caspase-1, resulting in elevation of il-1beta and il-18, with subsequently deteriorated renal injury. |
| PubMedID- 20215410 | In this species, hyperuricemia is associated with gout, nephropathy, and increased cardiovascular disease risk. |
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