eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hypertriglyceridemia |
| Comorbidity | C0004153|atherosclerosis |
| Sentences | 3 |
| PubMedID- 25836672 | The overexpression of human apo ciii in mice, rabbits and pigs has been shown to reduce lipoprotein lipase (lpl) activity and lead to hypertriglyceridemia, which is associated with atherosclerosis (ding et al., 2011; ito et al., 1990; wei et al., 2012). |
| PubMedID- 22129523 | Since the relationship of hypertriglyceridemia with atherosclerosis is not as clear as that of hypercholesterolemia, and since type i and v hyperlipoproteinemia are relatively rare, few guidelines for their diagnosis and treatment have been established; however, type i and v hyperlipoproteinemia are clinically important as underlying disorders of acute pancreatitis, and appropriate management is necessary to prevent or treat such complications. |
| PubMedID- 24667131 | Another possible reason for the early progression of atherosclerosis in hypertriglyceridemia may be the presence of small dense ldl. |
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