eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperthermia |
| Comorbidity | C0024530|plasmodium infection |
| Sentences | 2 |
| PubMedID- 26573620 | Case definition was established according to the sivigila protocol in which a malaria case is a patient having visited malaria endemic areas, in this case urban or peri-urban settings, in the 15 days prior to the current or recent febrile episode (>37.5 °c) with plasmodium infection confirmed either by thick blood smear (tbs) or rapid diagnostic test (rdt). |
| PubMedID- 24743880 | These findings offer mechanistic insights into several long-standing clinical observations in malaria including the high incidence of asymptomatic p. falciparum infection in endemic areas [69], reduced fever with repeated experimental plasmodium infections in humans [83], the rapid acquisition of immunity to severe malaria [50], the rapid loss of clinical immunity to febrile malaria in the absence of ongoing p. falciparum exposure [6] and plasmodium-induced hetero-tolerance to endotoxin challenge [25]. |
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