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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperthermia
Comorbidity C0018799|heart disease
Sentences 5
PubMedID- 21366959 Rheumatic heart disease is a sequel of rheumatic fever results from an untreated strep throat causing damage of the heart valves.
PubMedID- 22685225 Rheumatic fever complicated by rheumatic heart disease (rhd) remains a major contributor to morbidity and premature death among the socioeconomically underprivileged working age population of developing countries.1 rhd results from an autoimmune response due to molecular mimicry between the m-protein on the group a β-haemolytic streptococci cell membrane and cardiac myosin eventually leading to valvular damage.2 high prevalence rates of acute rheumatic fever (arf) and rhd have been reported from different geographic regions around the world such as southeast asia, the western pacific and africa that share demographic characteristics determined by poverty and limited access to healthcare resources.3 the burden of rhd is likely to escalate in these countries due to increasing urbanisation and overcrowding.
PubMedID- 22276281 Discussion: recurrent episodes of acute rheumatic fever may lead to rheumatic heart disease.
PubMedID- 23273191 Streptococcus pyogenes infection in human, causes initially pharyngitis due to inhalation of aerosols emitted by infected persons, develops rheumatic fever which leads to the rheumatic heart disease (damage of heart valves).
PubMedID- 20356787 Background: acute rheumatic fever, leading to rheumatic heart disease (rhd), is rare in australia except amongst aboriginal and torres strait islander people.

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