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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperthermia
Comorbidity C0001752|african swine fever
Sentences 20
PubMedID- 24406022 African swine fever endemicity in domestic pig populations in africa may therefore be the result of cycles involving repeated virus introduction from wild suid reservoirs, sustained virus spread within domestic pig populations, or a combination of both.
PubMedID- 24567878 A serious outbreak of african swine fever occurred in brazil in 1978, and caused huge economic losses to the country before it was eradicated in 1984. intensive epidemiological work was carried out by researchers from various brazilian and international institutions, involving a number of public authorities.
PubMedID- 21655242 African swine fever (asf) is an acute haemorrhagic fever caused by african swine fever virus (asfv), genus asfivirus, family asfarviridae, which can cause mortality approaching 100% in domestic pigs.
PubMedID- 22952450 African swine fever virus also targets tnfα-induced gene expression in infected-mφs by a mechanism involving the viral protein a238l [64].
PubMedID- 21122227 That same year, pcr and sequence analysis identified african swine fever virus in samples from 3 dead female wild boars in northwestern iran.
PubMedID- 24399914 Tom40 is required for replication of african swine fever virus in cultured human cells (chang et al.
PubMedID- 21192854 African swine fever (asf) is a disease caused by a dna virus in the family asfarviridae.
PubMedID- 20617142 For example, african swine fever virus, from another family of large dna viruses, causes a hemorrhagic disease in domestic pigs and encodes a number of genes that modulate the host immune response.
PubMedID- 24618592 For example, african swine fever virus (asfv) regulates nf-κb activity in a biphasic manner, where virus-induced nf-κb activation is initially inhibited by the early viral protein, a238l, that acts as a degradation-resistant i-κb homologue [35].
PubMedID- 21470447 African swine fever is widespread in africa but has occasionally been introduced into other continents.
PubMedID- 22219660 African swine fever has been reported in africa since the 1890's and is endemic in most parts of sub-saharan africa where transmission appears in three different forms; a sylvatic cycle, a domestic pig cycle and a pig-tick cycle [128, 129].
PubMedID- 20008386 African swine fever has caused severe losses to pig production in many african countries over the past decade.
PubMedID- 22479554 Moreover, the african swine fever virus protein, a238l has been shown to inhibit inflammatory gene expression in infected macrophages by binding to calcineurin and inhibiting nfat-dependent gene expression [50].
PubMedID- 25926829 African swine fever outbreaks in sardinia were spatially clustered, as indicated by the two significant clusters found with the bernoulli scan statistic model (figure 2) and by the much larger value of the dic when the spatially structured random effect si was removed from the model (dic = 408.96), compared with the model with si implemented on it (dic = 267.00).
PubMedID- 22764100 African swine fever virus (asfv) is a double-stranded large dna virus that induces an acute disease of swine in which apoptosis has a central role in pathogenesis.
PubMedID- 21118485 African swine fever (asf) is one of the most serious diseases in domestic pigs.
PubMedID- 19793538 This immunopathogenic mechanism also seems to be used by other leucopenic viruses, such as dengue virus, african swine fever virus and ebola virus but isg induction is generally reduced in these viruses, unlike csfv, by highly virulent strains compared to those of low virulence, suggesting that csfv causes a variant ifn response subversion [7, 16, 46].
PubMedID- 21994622 For example, baculovirus, african swine fever virus, herpes simplex virus and vaccinia virus incorporate lipid-modified ubiquitin in their envelopes [25,29–31].
PubMedID- 24369729 African swine fever (asf) is a viral disease with a devastating impact on the pig industry in sub-saharan africa [1].
PubMedID- 22935221 African swine fever (asf) is one of the most devastating diseases of swine due to the high mortality caused (mainly in the hyper-acute and acute forms of the disease), the absence of effective vaccine, and the severe trade restrictions associated with its presence in the affected areas.

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