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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperprolactinemia
Comorbidity C0033375|prolactinomas
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PubMedID- 25248588 In patients with prolactinomas the primary cause of hyperprolactinemia is excessive and autonomic production of prolactin by lactotroph cells.
PubMedID- 25799562 Clinical cases of hyperprolactinaemia associated with prolactinomas report low testosterone, decreased libido and erectile dysfunction [54] as well as low sperm count [55].
PubMedID- 20871665 In children and adolescents, hyperprolactinemia resulting from prolactinomas, which are rare, can result in galactorrhea, amenorrhea, gynecomastia, and maturational delay with growth failure [12].

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