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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperparathyroidism
Comorbidity C1561644|chronic kidney disease (ckd)
Sentences 15
PubMedID- 23713879 Paricalcitol is a synthetic vitamin d2 agonist of the vdr approved for the prevention and treatment of secondary hyperparathyroidism associated with chronic kidney disease (ckd).
PubMedID- 22930877 Secondary hyperparathyroidism in patients with chronic kidney disease (ckd) is common and usually caused by associated metabolic abnormalities, in particular, hypocalcaemia and hyperphosphataemia.
PubMedID- 26429172 Vascular calcifications represent a severe complication of secondary hyperparathyroidism in patients with chronic kidney disease (ckd) stage 5.
PubMedID- 25984155 Hyperphosphataemia is an established risk factor for cardiovascular mortality, renal osteodystrophy and secondary hyperparathyroidism in patients with end-stage chronic kidney disease (ckd) under renal replacement therapy.
PubMedID- 20090879 The calcimimetic, cinacalcet, is approved for treating secondary hyperparathyroidism (shpt) in patients with chronic kidney disease (ckd) on dialysis.
PubMedID- 25949433 This study aims to highlight the challenges in the diagnosis of hyperparathyroidism (hpt) in patients with advanced chronic kidney disease (ckd).
PubMedID- 22997972 Background: secondary hyperparathyroidism develops frequently with chronic kidney disease (ckd) and is associated with poor outcome.
PubMedID- 25028644 The development of calcimimetics, which are synthetic allosteric modulators of the calcium-sensing receptor (car), has been a breakthrough in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (ckd).
PubMedID- 20056760 Background and objectives: the optimal treatment of secondary hyperparathyroidism in chronic kidney disease (ckd) is unknown.
PubMedID- 22015443 Background: the recently developed non-invasive high-intensity focussed ultrasound (hifu) technique for the destruction of parathyroid adenomas could also be of interest for the treatment of secondary hyperparathyroidism (shp) in patients with chronic kidney disease (ckd).
PubMedID- 21076444 Secondary hyperparathyroidism in chronic kidney disease (ckd) develops in response to disturbances in calcium and phosphate metabolism associated with ckd, including fgf23 and klotho.
PubMedID- 21885174 Background: the efficacy of 25-hydroxyvitamin d (25[oh]d) supplementation versus vitamin d receptor activators for the treatment of secondary hyperparathyroidism (shpt) in patients with chronic kidney disease (ckd) stages 3 or 4 and vitamin d deficiency is unclear.
PubMedID- 25446887 Vitamin d insufficiency is prevalent in chronic kidney disease (ckd) and associated with secondary hyperparathyroidism (shpt) and increased risk of bone and vascular disease.
PubMedID- 23960343 This study was carried out to evaluate the efficacy and safety of doxercalciferol as therapy for secondary hyperparathyroidism (shpt) in patients with chronic kidney disease (ckd) stage 4 in a prospective clinical trial.
PubMedID- 23140920 Considering its low incidence rate of long-term relapse, "presumed" total parathyroidectomy without autotrasplantation (tp) may be indicated for secondary hyperparathyroidism (2hpt) in patients with chronic kidney disease (ckd), not eligible for kidney transplantation.

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