eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperparathyroidism |
| Comorbidity | C0024523|malabsorption |
| Sentences | 2 |
| PubMedID- 22593794 | Bone loss is explained by the overproduction of cytokines il-1 alpha, il-1 beta and tnf-alpha which is further accelerated by hyperparathyroidism connected with malabsorption of calcium and vitamin d. interaction of both these mechanisms increases bone resorption and activates bone loss. |
| PubMedID- 24008401 | Results: mechanisms identified to contribute to alterations in bone metabolism after bypass surgery include: decreased mechanical loading, calcium and vitamin d malabsorption with secondary hyperparathyroidism, deficiency in other nutrients, in addition to alterations in adipokines, gonadal steroids, and gut-derived hormones favoring bone loss, with the exception of serotonin and glucagon-like peptide-1. |
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