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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperemesis gravidarum
Comorbidity C0020550|hyperthyroidism
Sentences 3
PubMedID- 21570635 The trab test is therefore of most value in ambiguous clinical scenarios such as in the differential diagnosis of unilateral exophthalmos, euthyroid graves' ophthalmopathy, subclinical hyperthyroidism, thyrotoxicosis associated with hyperemesis gravidarum, amiodarone-induced thyrotoxicosis and painless thyroiditis.
PubMedID- 22419883 Gestational transient hyperthyroidism (gth) is associated with hyperemesis gravidarum, commonly presenting with elevated levels of ft4 and suppressed levels of tsh.
PubMedID- 25767463 A unique family with recurrent gestational hyperthyroidism associated with hyperemesis gravidarum was found to have a mutation in the ecd of the tshr that made it responsive to normal levels of hcg (122).

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