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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hypercalcemia
Comorbidity C0026764|multiple myeloma
Sentences 7
PubMedID- 25128013 Denosumab for the management of hypercalcemia of malignancy in patients with multiple myeloma and renal dysfunction.
PubMedID- 21915243 Interestingly, aminobisphosphonates (abs) which are synthetic compounds commonly used to treat bone disease and hypercalcemia in patients with multiple myeloma, breast or prostate cancer, have been identified also as antigens for γδ t cells, indicating these molecules as immunomodulating factors [21]–[26].
PubMedID- 24743202 Bisphosphonates(bps)have been widely used for the treatment of hypercalcemia associated with cancer, multiple myeloma bone diseases, and bone metastasis of solid cancers.
PubMedID- 24334568 It is the most common primary bone malignancy, and the extensive osteoclastic bone resorption common in multiple myeloma is associated with hypercalcemia in as many as one-third of patients.
PubMedID- 21605111 Calciphylaxis, occurring 10 weeks after hypercalcaemia, in a patient with multiple myeloma.
PubMedID- 22073517 multiple myeloma with hypercalcemia and chloride resistant metabolic alkalosis.
PubMedID- 22082730 Introduction: osteonecrosis of the jaw (onj) is an emerging condition in patients undergoing long-term administration of bisphosphonates (bp) for the treatment of osteoporosis and hypercalcaemia associated with malignancy, multiple myeloma, and metastatic breast and prostate cancers.

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