eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperaldosteronism |
| Comorbidity | C0042373|vascular disease |
| Sentences | 2 |
| PubMedID- 25462268 | 1-phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols and related compounds were synthesized and evaluated for inhibition of aldosterone synthase (cyp11b2), a potential target for cardiovascular diseases associated with elevated plasma aldosterone levels like congestive heart failure and myocardial fibrosis. |
| PubMedID- 21677812 | [3] excess renin secretion can produce secondary aldosteronism, as occurs with renal vascular disease, aortic coarctation, renal parenchymal disease associated with inflammation or scarring or renin-secreting tumors. |
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