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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperaldosteronism
Comorbidity C0020456|hyperglycemia
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PubMedID- 23506284 Introduction: expression of serum-and-glucocorticoid-inducible kinase-1 (sgk1) is low in most cells, but dramatically increases under certain pathophysiological conditions, such as glucocorticoid or mineralocorticoid excess, inflammation with tgfbeta release, hyperglycemia, cell shrinkage and ischemia.

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