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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperaldosteronism
Comorbidity C0007222|cardiovascular diseases
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PubMedID- 25462268 1-phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols and related compounds were synthesized and evaluated for inhibition of aldosterone synthase (cyp11b2), a potential target for cardiovascular diseases associated with elevated plasma aldosterone levels like congestive heart failure and myocardial fibrosis.

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