eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hunter syndrome |
| Comorbidity | C0007682|cns disease |
| Sentences | 2 |
| PubMedID- 25836678 | In addition, the long residence time of i2s in the csf after it administration should provide the time needed for the i2s to penetrate the brain tissue and degrade the accumulated glycosaminoglycans, which may have an impact on the progression of cns disease manifestations in patients with hunter syndrome. |
| PubMedID- 21225451 | These suggest that developing a cure for the cns diseases of mps iiib and other similar disorders may require more than the simple restoration of the absent or deficient lysosomal enzyme activity. |
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