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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hepatitis a
Comorbidity C0023890|liver cirrhosis
Sentences 5
PubMedID- 24391361 It causes acute and chronic hepatitis and is amain cause of liver cirrhosis and hepatocellular carcinoma [2].hcv belongs to flaviviridae family with a positive-sense singlestrandedrna genome which encodes three structural proteins(core, e1, e2) and six non-structural pmroteins (ns2, ns3,ns4a, ns4b, ns5a & ns5b) [3].
PubMedID- 24025913 W4p/r mutants were found to be significantly related to severe liver diseases (hepatocellular carcinoma [hcc] and liver cirrhosis, 12.4% [19/153] of patients, versus chronic hepatitis and asymptomatic carriage, 1.1% [1/94] of patients) (p < 0.001).
PubMedID- 24816397 Hcv causes chronic hepatitis and further leads to liver cirrhosis and hepatocellular carcinoma [3], [13], [14].
PubMedID- 20938626 The great majority of these cases in germany can be attributed to chronic liver disease (alcohol, viral hepatitis among others), which lead to development of liver cirrhosis and ultimately to hepatocellular carcinoma.
PubMedID- 22799897 A 32-year-old man who was a hepatitis b carrier with child-pugh a liver cirrhosis presented with abdominal fullness of three-month duration.

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