eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hemophilia |
| Comorbidity | C0022408|arthropathy |
| Sentences | 9 |
| PubMedID- 19943875 | Background: prophylactic factor (f)viii has been shown to reduce bleeds and arthropathy in patients with severe hemophilia a. |
| PubMedID- 21070500 | The aim of this study was to evaluate the effectiveness of primary prophylaxis therapy in preventing the development of arthropathy in children with severe haemophilia a or b. |
| PubMedID- 24589126 | The current practice of using tertiary prophylaxis, in the presence of established joint arthropathy, in adults with haemophilia b is not well characterized. |
| PubMedID- 21255253 | Conclusion: this randomized trial confirms the efficacy of prophylaxis in preventing bleeds and arthropathy in children with hemophilia, particularly when it is initiated early in life. |
| PubMedID- 23231016 | We recently showed in a single centre trial that low-dose secondary prophylaxis in severe/moderate haemophilia patients with arthropathy is feasible and beneficial. |
| PubMedID- 24286243 | A different explanation for long-term arthropathy in haemophilia, following multiple bleedings, may be a secondary development of auto-immune joint disease. |
| PubMedID- 22778972 | This randomized trial confirmed the efficacy of prophylaxis in preventing bleeds and arthropathy in children with hemophilia, particularly when it is initiated early in life. |
| PubMedID- 24022804 | arthropathy in patients with moderate hemophilia a: a systematic review of the literature. |
| PubMedID- 23906463 | [long-term low-dose secondary prophylaxis for severe and moderate hemophilia children with arthropathy in china: a single-center observation study]. |
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