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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hemolytic anemia
Comorbidity C0040034|thrombocytopenia
Sentences 28
PubMedID- 21295897 We report the first case to our knowledge of a patient who developed an acute decrease in kidney function, nonimmune microangiopathic hemolytic anemia with schistocytes, and thrombocytopenia after 4 intravitreal injections of ranibizumab.
PubMedID- 22929300 59. thrombocytopenia associated with mechanical hemolytic anemia should suggest tma, even in the absence of organ failure (strong agreement).
PubMedID- 23943710 A congenital or acquired deficiency of adamts-13 can result in accumulation of the ultralarge vwf multimers leading to microangiopathic thromboses and severe thrombocytopenia with resultant hemolytic anemia and thrombotic sequelae.6 in the rare familial forms of ttp, mutations of the adamts-13 gene can be found resulting in significant risk of ttp in pregnancy in affected women.6 acquired ttp is postulated to be secondary to viral infections that trigger production of antibodies targeted against adamts-13.7 women with acquired ttp also have a high risk of recurrence in a subsequent pregnancy.6 it has been proposed that specific proteins found in the placental circulation serve as antigens that trigger maternal antibody production against adamts-13.
PubMedID- 23304632 The traditional diagnostic criteria for this syndrome include hemolytic anemia with fragmented erythrocytes, thrombocytopenia, and renal failure [1].
PubMedID- 21776377 Laboratory findings revealed thrombocytopenia with hemolytic anemia.
PubMedID- 21151550 Peripheral blood smear examination revealed schistocytes and thrombocytopenia consistent with microangiopathic hemolytic anemia (fig.
PubMedID- 23405542 Evan's syndrome, i.e., autoimmune haemolytic anaemia with thrombocytopenia is however a very rare occurrence inspite of high direct coomb's test positivity in hiv patients.
PubMedID- 23842487 Background: hemolytic anemia with thrombocytopenia and schistocytosis is suggestive of thrombotic thrombocytopenic purpura (ttp).
PubMedID- 21559455 The criteria for hus diagnosis were microangiopathic hemolytic anemia with schizocytes, thrombocytopenia (platelet count <150×109/l) and acute renal failure (serum creatinine level higher than the normal values considering the age of the patient).
PubMedID- 21961487 He was diagnosed to have es at the age of 8, during another bout of thrombocytopenia, this time associated with coombs-positive hemolytic anemia.
PubMedID- 20636987 Objective: to identify and characterize the syndrome of immune-mediated hemolytic anemia (imha) with concurrent severe thrombocytopenia (
PubMedID- 24013519 A mixed-type autoimmune hemolytic anemia with immune thrombocytopenia related with myositis and post-transplantation lymphoproliferative disorder.
PubMedID- 22374533 It is important to suspect ttp when hemolytic anemia with thrombocytopenia is observed, and to check the activity and antigen of adamts13 immediately for the diagnosis.
PubMedID- 23602056 thrombocytopenia together with microangiopathic hemolytic anemia is mandatory for the diagnosis of ttp and if these two criteria met in a patient, tpe should be performed immediately.
PubMedID- 21772952 Evans syndrome (es) is an autoimmune disorder characterized by thrombocytopenia and/or neutropenia associated with hemolytic anemia (aha).1–3 it is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymph-proliferative disorders.4 standard treatment consists of transfusions, corticosteroids and immunoglobulins (ivig); second-line treatment in es evolved over the last decade, and includes at present anti-cd20 rituximab, vincristine, alkalizing agents, mycophenolate mofetil (mmf) or cyclosporine (cya).5–6,8–14 long-term remissions induced by splenectomy are less frequent than in uncomplicated immune thrombocytopenia purpura (itp).
PubMedID- 20031296 Evans' syndrome, the coexistence of immune thrombocytopenia (itp) with autoimmune haemolytic anaemia (aiha), is rare in pregnancy, with a few published cases.
PubMedID- 20056203 Result(s): both patients developed a very rare complication after surgery of severe thrombocytopenia with microangiopathic hemolytic anemia leading to acute renal failure.
PubMedID- 23989401 For thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (ttp-hus) the diagnosis of coombs negative hemolytic anemia together with thrombocytopenia should lead to the detection of fragmentocytes in peripheral blood smears.
PubMedID- 21151638 [8] reported a case of thrombocytopenia associated with hemolytic anemia in a patient with intracardiac metastasis originating from a testicular teratoma.
PubMedID- 23961497 The overall impression on hematological examination was hemolytic anemia with thrombocytopenia and reactive marrow hyperplasia.
PubMedID- 24490094 There are many reported cases of hemolytic anemia with or without thrombocytopenia in gastric cancer.
PubMedID- 25859345 In general, although tma may be renal limited, hypertension and a more generalized microangiopathic haemolytic anaemia with thrombocytopenia also occur.
PubMedID- 23827373 Hemolytic and uremic syndrome (hus) is a classical form of thrombotic microangiopathies characterized by the association of hemolytic anemia with schizocytes, thrombocytopenia, and acute renal failure.
PubMedID- 25821808 Eryptosis is triggered by hemolytic uremic syndrome (hus), characterized by hemolytic anemia with fragmented erythrocytes, thrombocytopenia, and acute renal failure [198].
PubMedID- 20436664 Thrombotic microangiopathies (tma) represent a rare and heterogeneous group of diseases defined by microangiopathic hemolytic anemia with peripheral thrombocytopenia and organ failure of variable severity.
PubMedID- 20948827 It is characterised by microangiopathic haemolytic anaemia with thrombocytopenia and renal failure and is distinguished from classical diarrhoea-associated hus typically occurring in childhood (caused by shiga-toxin-producing bacteria and with a good prognosis; >90% children recover normal renal function with supportive therapy) and characterized by its chronic and relapsing course.
PubMedID- 20399168 hemolytic anemia with schistocytes, thrombocytopenia without evidence of disseminated intravascular coagulation, and renal failure are consistently found.
PubMedID- 20331741 Recognition of cancer-associated microangiopathic hemolytic anemia with thrombocytopenia (ca-mha) is paramount to avoid inappropriate pe therapy and delays in cancer-specific chemotherapy.

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