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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hemolytic anemia
Comorbidity C0027022|myeloproliferative disorders
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PubMedID- 24575292 In our case the differential diagnosis process began by considering the broad categories of disease that presented with hepatosplenomegaly: anatomical abnormalities, congestion, infection, hematologic disorders, and infiltrative processes .although hematologic disorders could explain the organomegaly, several of these (including chronic hemolytic anemia, disorders associated with extramedullary hematopoiesis, myeloproliferative disorders, and sickle-cell disease) were ruled out because of the absence of other key signs such as jaundice, abnormal hemoglobin electrophoresis, painful crisis and leukocytosis.

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