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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hemolytic anemia
Comorbidity C0024790|paroxysmal nocturnal hemoglobinuria
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PubMedID- 24369265 [autoimmune hemolytic anemia with a paroxysmal nocturnal hemoglobinuria-like defect: report of one case].
PubMedID- 22851928 In the present, replacement therapy of c1-inhibitor is also another established treatment for hereditary angioedema in addition to anti-c5 antibodies for c-dependent hemolytic anemia in patients with paroxysmal nocturnal hemoglobinuria, respectively [155,156].
PubMedID- 26043387 paroxysmal nocturnal hemoglobinuria is manifests with a chronic hemolytic anemia from uncontrolled complement activation, a propensity for thrombosis and marrow failure.

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