eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hemolytic anemia |
| Comorbidity | C0017920|g6pd deficiency |
| Sentences | 8 |
| PubMedID- 20175930 | Higher doses of primaquine can cause haemolytic anaemia in individuals with g6pd deficiency, but the lower doses used in this programme are thought to be safe, based on extensive experience in malaria elimination campaigns in past decades. |
| PubMedID- 24052930 | In fact, case reports of g6pd deficiency with severe hemolytic anemia published in japan often describe the family history of foreign mothers (shimomura et al. |
| PubMedID- 24259700 | Methylene blue should not be used as an antidote because it may worsen hemolytic anemia in patients with g6pd deficiency. |
| PubMedID- 22607348 | Primaquine has been associated with acute haemolytic anaemia in patients with g6pd deficiency and, therefore, knowledge of the prevalence and geographical distribution of this inherited blood condition in p. vivax endemic areas is important [49]. |
| PubMedID- 25748035 | The hemolytic anemia in g6pd deficiency is usually triggered by oxidative stress, but the mechanism remains uncertain. |
| PubMedID- 24913163 | In a novel mouse model of hemolytic anemia associated with human g6pd deficiency, it was also demonstrated that (-)-(r)-pq was less hemolytic than (+)-(s)-pq for the g6pd-deficient human red cells engrafted in the nod-scid mice. |
| PubMedID- 25885097 | Being aware of primaquine inducing acute haemolytic anaemia, participants with g6pd deficiency were exempted from taking part in a study that used primaquine to radically clear malaria parasites [13]. |
| PubMedID- 24223971 | It has also been demonstrated that infections caused by certain viruses, such as hepatitis viruses (a, b, and e) and cytomegalovirus, were associated with hemolytic anemia in patients with g6pd deficiency [8,9]. |
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