eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | heavy chain disease |
| Comorbidity | C0021071|alpha-heavy chain disease |
| Sentences | 1 |
| PubMedID- 22708049 | Alpha-heavy chain disease is frequently seen in mediterranean countries and middle east.4,10,11 it can involve stomach, colon, liver, peritoneum, periaortic and cervical lymph nodes.15 the involvement of bone marrow and increase of immunoglobulin a level in α-hcd is very rare.14 the histological findings of α-hcd have been classified into three distinct stages: stages a includes mature plasmacytic or lymphoplasmacytic infiltration of mucosal lamina propria and mesenteric lymph nodes. |
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