eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hartnup disease |
| Comorbidity | C0029456|osteoporosis |
| Sentences | 1 |
| PubMedID- 24039120 | Simulation of postmenopausal osteoporosis (pmo) with disease initiation at tpmo,ini = 0: (a) prescribed temporal evolutions of the reduction factor of the disease-related rankl production rate, , and of the mechanoresponsiveness reduction factor, , (b) model-predicted evolutions of the concentrations of active osteoclasts, , and active osteoblasts, , normalized with respect to the concentration before onset of pmo, and , (c) the increase of the vascular porosity of osteoporotic cortical bone over time, δfvas(t), simulated by our model, compared with corresponding experimental results, and (d) the phase diagram comparing bone resorption versus bone formation responses associated to the simulated porosity increase of osteoporotic cortical bone; the arrows indicate path directions. |
Page: 1