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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hartnup disease
Comorbidity C0006142|breast cancer
Sentences 14
PubMedID- 22935625 Notably, in head and neck and breast cancers, levels of eif4e correlate with disease progression and poor prognosis [8, 10, 18, 23].
PubMedID- 21232165 In the families with at least two breast cancers, all of them with disease onset over the age of 50 years, the detection rate was 5% for brca2 and 0% for brca1.
PubMedID- 24648347 Reduced expression of both cd24 and pawr was associated with disease progression in patients with breast cancer, and their expression was suppressed in metastatic tissues.
PubMedID- 26237143 Three other similarly designed trials investigated the effect of delayed vs. upfront zoledronic acid on bone mineral density in postmenopausal breast cancer patients, with disease recurrence as a secondary endpoint (z-fast, e-zo-fast and zo-fast) [36,37,38].
PubMedID- 25767772 Both ctcs and dtcs have been detected in breast cancer patients with disease states ranging from ductal carcinoma in situ to mbc (55–60), and their detection is generally associated with a poor prognosis.
PubMedID- 25674003 In our study, we combined all eligible studies on the relationship of igf-1r expression in breast cancers with disease-free survival (dfs) and/or overall survival (os)/breast cancer-specific survival (bcss).
PubMedID- 25613376 In epithelial tissues, rest acts as a tumor suppressor and in breast cancer, loss of rest is associated with disease recurrence and poor prognosis.
PubMedID- 24122389 Clinical studies have shown that single-agent capecitabine was an active and tolerable treatment for metastatic breast cancer (mbc) with disease progression during and after anthracycline and taxane therapy, achieving response rates of 20–29 % and a median survival in excess of 1 year [10, 11].
PubMedID- 23150342 In breast cancer, increased expression of gamma-synuclein correlates with disease progression.
PubMedID- 23552639 Furthermore, many studies have reported that elevation of src activity in human tumors including breast cancer correlates with disease stage and poor prognosis.46, 47 hence, future profiling of the brk activation in a large cohort of breast tumor samples may enable the use of brk activation as a diagnostic or prognostic marker, and inhibition of brk activity or activation as a viable therapeutic strategy in breast cancer treatment.
PubMedID- 24098745 In the present study, we examined the association of menopausal symptoms experienced by breast cancer patients with disease-specific outcomes such as recurrence in the shanghai breast cancer survival study (sbcss).
PubMedID- 24762669 Clinically, erk5 protein is overexpressed in early stage breast cancer and associated with disease free survival [45].
PubMedID- 25880737 Number of negative lymph nodes is associated with disease-free survival in patients with breast cancer.
PubMedID- 24637461 breast cancer patients with disease of similar stage and grade often respond differently to therapy resulting in disparate clinical outcomes.

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